BIOMER DELIVERS A STENT COATING TO ACCELERATE THE HEALING PROCESS AND REDUCE COMPLICATIONS
Lead technology: accelerateTM AT Coating
Nature prefers order and balance
Disruptions to the natural order, through disease or physical intervention, stimulate the body’s internal defence mechanism at the cellular level.
In the case of coronary stenting, the stent structure is designed to restore blood flow by providing a physical scaffold to maintain vessel patency with the minimal vessel wall contact. Where the stent strut contacts the arterial wall, they exert a force on the tissue further disrupting the already compromised surface.
Our stent coating is designed to restore the natural balance by encouraging *reendothelialisation of the vessel surface post stent deployment, which in turn accelerates the healing process and thereby results in fewer complications.
*State of the art paper
Role of the endothelium in modulating neointimal formation
Nicholas Kipshidze, MD, PhD, FACC*,*, George Dangas, MD, PhD, FACC*, Mykola Tsapenko, MD, PhD , Jeffrey Moses, MD, FACC*, Martin B. Leon, MD, FACC*, Michael Kutryk, MD and Patrick Serruys, MD, PhD, FACC
The accelerateTM AT Coating is a novel, biodurable, biocompatible, polymeric coating designed to modulate the adhesion and proliferation response of vascular cells. The proprietary surface chemistry provides extracellular microenvironments that mimic the regulatory properties of natural extracellular matrices.
Select polymers from the accelerateTM Technology range have undergone extensive in-vitro and preclinical testing, conducted through collaborations with leading academic and clinical centres worldwide.
The accelerateTM AT Coating for coronary stenting is currently awaiting CE mark approval following the successful completion of FIH safety studies (HARTS 1).
Angiography before and after PCI and at 6 months F/U